Researchers at several different centers across Austria determine that CRP levels (C-Reactive Protein) could be a good indicator as to whether radical surgery for Mesothelioma will actually help the patient and extend life.
CRP is a protein that is made in the liver during times of acute illness and inflammation. This study in Austria analyzed 115 patients with a confirmed Mesothelioma diagnosis. Any patient with an active infectious disease diagnosis was excluded from the study. CRP levels were measured in each patient prior to receiving multiple modality treatments.
Researchers found that patients with normal CRP levels had much better results after receiving multiple modality treatments and even surgery in some cases. Mesothelioma patients who had elevated CRP levels did not respond to treatment well.
Patients with CRP levels within normal ranges actually ended up with extended life benefits. Patients who started treatment with increased CRP levels did not see any real benefit with treatment.
Researchers, physicians, and patients have difficult decisions to make when it comes to the treatment of Mesothelioma. This cancer is believed to be related to asbestos exposure. It is an extremely aggressive form of cancer that attacks the mesothelium in the body. The mesothelium is the double lining that covers the organs in the body. Mesothelioma often times begins in the peritoneum (mesothelium that covers the abdominal cavity) or the pleura (lining that covers the lungs). This type of cancer metastasizes to other areas of the body quickly. It can end up spreading to other mesothelium and to the organs that are covered by infected and cancerous lining.
Surgery to treat Mesothelioma is extremely risky. Many people do not make it through the complications that can occur following the surgery. This study can help to determine the best treatment options for patients with Mesothelioma. It gives the people involved one more piece of knowledge to help determine the outcome of treatment.
Early and intense multiple modality treatment is the best route for Mesothelioma sufferers. However, since the cancer grows so quickly, sometimes it is not even diagnosed early on. Thus, it becomes more difficult to treat the cancer.
If CRP levels can be used to help determine the outcome of treatment, doctors will be able to advise on the best treatment options based on the way the body is currently responding to the stress. If acute inflammation and extreme stress is already registering based on increased CRP levels, alternative treatment options may be determined that do not stress the body as much.
Currently, there is no cure for Mesothelioma. However, with continued research, it is possible to find better treatment options for those who are faced with Mesothelioma.